I know Butterbur sounds like it is for the skin. Like a fancy skincare product for wrinkles or something. But no, it is a herbal migraine treatment. I happen to be allergic to it, but it does have research behind it for beneficial results.
The development of a standardized extract of the rhizome of butterbur (Petasites hybridus) has led to a new clinical approach to the management of migraine headache. Two clinical trials with a standardized CO2 extract (Petadolex[R], Weber & Weber International GmbH & Co., Germany) have successfully demonstrated the extractis ability to safely and effectively reduce the frequency and intensity of migraine headaches…..
… The leaves, rhizome, and roots of butterbur contain a mixture of eremophilan-type sesquiterpenes consisting primarily of petasin and isopetasin. (4) According to phytotherapy textbooks, petasin and isopetasin have both spasmolytic and analgesic actions. (5) These active constituents also inhibit leukotriene synthesis, which may also contribute to butterburis antispasmodic and anti-inflammatory actions. (6)
FindArticles – Standardized butterbur extract Petadolex®—herbal approach to migraine prophylaxis
Townsend Letter for Doctors and Patients, Oct, 2002, by Donald J. Brown