My mom read an article on MVP and she thought it sounded just like me, and that I should take magnesium. I told her it had crossed my mind back in the day as well, and maybe I do. But even so, there are two other reasons to take magnesium: migraines and FMS. So I bought some and am starting slow and working my way up. I am hoping it will help with the muscles spasms at the least.
It looks like magnesium supplements may work as a migraine preventative and magnesium deficiency can cause migraines. Worth a shot.
Should You Be Taking Magnesium?
Two doubleblind studies have shown that magnesium supplementation may reduce the frequency of migraine. In research studies, we have found that magnesium levels affect serotonin receptors, and also have an effect on nitric oxide synthesis and release, as well as on NMDA receptors—all brain structures and chemicals suspected to be important in migraine. In small studies, both migraine and cluster headache patients have responded acutely to intravenous magnesium. In a larger double-blind controlled study, the treatment group, receiving 600mg of magnesium for a 12 week period, experienced a 41.6% reduction in headaches as compared to only 15.8% reduction in migraine headaches in the placebo group.– The Daily Headache
Which leads to Reason Number 2-
When you have a Fibromyalgia migraine combo platter you find a bit of an additional pattern. Often people with FMS are deficient in magnesium, simply because of the sleep disorders, less growth hormone, and therefore less magnesium.
Magnesium deficiency is therefore one of many problems in people with fibromyalgia which is due to or influenced by the sleep disturbance. So while it’s possible to attain some benefit from taking magnesium, treating any sleep disorder is just as helpful, if not more so.
Magnesium is extremely important to many functions in the body, which is why a deficiency can cause many different symptoms. It is most widely known for being needed for proper bone formation. With a deficiency, bones will be soft, and it can play a role in osteoporosis However, magnesium is also the activating mineral for at least 350 different enzymes in the body, more than any other mineral, so it is crucial for many of the metabolic functions in the body. Magnesium is necessary for almost all the enzymes that allow the glycolytic and Krebs cycles to turn the sugar and fat we eat into ATP. Low levels of ATP have commonly been found in people with fibromyalgia, and it is believed that this plays an important role in many of the fibromyalgia symptoms. Thus, a magnesium deficiency would definitely be a factor in worsening those symptoms.
Magnesium is extremely necessary for proper ATP synthesis, because ATP is stored in the body as a combination of magnesium and ATP, which is known as MgATP. ATP requires magnesium in order to be stable. Without magnesium, ATP would easily break down into other components, ADP and inorganic phosphate.
The brain heavily relies ATP for many functions. In fact, 20% of total body ATP is located in the brain. Thus, low levels of ATP can diminish brain cognitive functions, a common problem in people with fibromyalgia.
Adequate magnesium is necessary for proper muscle functioning. Magnesium deficiency promotes excessive muscle tension, leading to muscle spasms, tics, restlessness, and twitches. This is due to an imbalance of the ratio of calcium to magnesium, as calcium controls contraction, while magnesium controls relaxation. Plus, in fibromyalgia, changes are seen in the muscles, such as “significantly lower than normal phosphocreatine and ATP levels” and “values for phosphorylation potential … also were significantly reduced”:Role of magnesium in FMS