Study suggests migraine with aura people can have vidual abnormalities in-between attacks

3 (2)

Again a study finds there is in fact symptoms between migraines. One study had illustrated that photosensitivity persisted to a degree in some migraineurs after a migraine. Since I have daily migraines, wasn’t awed by this one, given I have pretty extreme photosensitivity all the time… but nonetheless it demonstrated the symptom persisted beyond the migraine event.

Common visual aura during a migraine attack

This study is more peculiar. In migraine with aura… do visual issues persist after the migraine event? In fact, they do.

“Researchers also recognize that migraine patients have symptoms in-between attacks – inter-ictal symptoms.  Could vision problems be one of these?

Researchers at The University of Melbourne in Australia did some in-depth study of 43 people, 17 with migraine, to find the answer.  And the answer was – yes.  Migraine patients do have visual abnormalities in-between attacks.

This testing was more than reading letters on the wall.  Researchers measured electrical responses of the retina, and used other tools to measure visual abnormalities.  They found that there was both retinal and cortical dysfunction, although it varied from patient to patient and could change over time.” Headache and migraine news

Perhaps a reason to keep getting your eyes checked. Although many of us with aura may ignore that because it is all ‘aura’ business, perhaps we might want to continue getting that checked regularly. Secondly a reason to keep track of possible symptoms between migraines. My persistent migraine auras have evolved over time and become quite distorting at times, one wonders if some of those ‘additions’ are because I get daily migraines. Either way these studies of how our brains are affected between attacks are getting pretty interesting.

Pubmed Abstract



In between migraine attacks, some people show visual field defects that are worse when measured closer to the end of a migraine event. In this cohort study, we consider whether electrophysiological responses correlate with visual field performance at different times post-migraine, and explore evidence for cortical versus retinal origin.


Twenty-six non-headache controls and 17 people with migraine performed three types of perimetry (static, flicker and blue-on-yellow) to assess different aspects of visual function at two visits conducted at different durations post-migraine. On the same days, the pattern electroretinogram (PERG) and visual evoked response (PVER) were recorded.


Migraine participants showed persistent, interictal, localised visual field loss, with greater deficits at the visit nearer to migraine offset. Spatial patterns of visual field defect consistent with retinal and cortical dysfunction were identified. The PERG was normal, whereas the PVER abnormality found did not change with time post-migraine and did not correlate with abnormal visual field performance.


Dysfunction on clinical tests of vision is common in between migraine attacks; however, the nature of the defect varies between individuals and can change with time. People with migraine show markers of both retinal and/or cortical dysfunction. Abnormal visual field sensitivity does not predict abnormality on electrophysiological testing.


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.